Sahar El Aidy is professor of microbiome engineering at the University of Amsterdam, where her laboratory investigates the impact of the gut microbiome on human health. Recognised by the Dutch Research Council (NWO) with an Athena Award for her “ground-breaking publications” and influential research communication, her recent major discoveries include a link between gut microbes and the efficacy of medication for Parkinson’s disease.
Where were you born, and how has this shaped who you are?
Born in Berlin, I moved to Egypt, my parents’ homeland, at the age of one. Despite my brief time in Germany, the values I encountered there – punctuality, order and efficiency – left a lasting impression on me. Growing up in Egypt, I often felt distinct in my seriousness and organisational skills, traits less common in the relaxed and communal Egyptian culture. Friends and family would comment on my precise nature, attributing it to my German beginnings.?In 2004, I relocated to the Netherlands to pursue an academic career. Here, my serious and organised demeanour found balance with the Dutch emphasis on pragmatism and progressiveness, complementing my Egyptian warmth and community spirit.
What attracted you to academia?
Both my parents are university professors, so academia was a natural and inspiring path for me. Their dedication to teaching and research deeply influenced my career choice. Additionally, I have always been passionate about travelling the world, a dream not easily accessible to many Egyptians. Observing my father achieve this dream through attending international conferences and academic collaborations further fuelled my desire to pursue academia.
Tell?us about your research on the gut microbiome.
We employ state-of-the-art analytical chemistry and microbiology methods to discover new chemical signals produced by gut bacteria. Using innovative ex vivo systems, we study how these microbes affect intestinal functions such as bowel movements, revealing that microbial metabolism of drugs can alter gut contractility. Our work also delves into the complex chemical interactions within the microbiota, illustrating how these chemicals influence microbial communities and gut health. I aim to develop therapies based on microbiota, particularly for conditions where the gut-brain axis is crucial. My research investigates how bacterial cells manage vital processes in response to environmental challenges?such as nutrient scarcity and examines the collective behaviour and distribution of bacterial populations within specific ecological niches.
What do you wish more people knew about the relationship between the gut microbiome and human health?
The gut microbiome is crucial because it plays a key role in digestion, immune function and mental health. A healthy gut microbiome helps break down food, absorb nutrients and protect against harmful pathogens. A disturbed gut microbiome can contribute to a range of health issues, including digestive disorders, weakened immunity and conditions?such as anxiety and depression. I wish more people understood that the gut microbiome affects nearly every aspect of our health. The bacteria in our gut produce chemicals that influence brain function, immune responses and even how our bodies respond to medications. Recognising the importance of a balanced gut microbiome can lead to better dietary choices, more informed healthcare decisions and improved overall health outcomes.
You’ve dedicated a lot of time?to science communication throughout your career. Why is it important to share your research with the broader public?
Engaging in science communication and outreach is fundamental for bridging the gap between scientific advancements and public understanding. It enforces a culture of curiosity, critical thinking and lifelong learning, which empowers individuals to make informed decisions in an increasingly complex world. It also inspires future generations of scientists, engineers, innovators and more. In my opinion, it’s crucial to communicate research on the microbiome to the broader public because understanding this complex system can have significant impacts on health, lifestyle choices and environmental sustainability. Empowering laypeople with knowledge about the microbiome can lead to informed decisions about diet, hygiene practices and medical treatments. Moreover, public awareness can drive support for research funding, policy changes and innovations in healthcare that benefit society as a whole.
What are the positives of life in academia?
The opportunity for intellectual exploration and discovery, the potential to make meaningful contributions to knowledge and society through research, and the chance to engage with like-minded colleagues and students who share a passion for learning. Additionally, academia often offers flexibility in work schedules and the ability to pursue diverse interests within one’s field.
And the negatives?
Academic life can come with challenges. These?can include high pressure to publish and secure funding, navigating the competitive nature of academic environments and balancing teaching, research and administrative responsibilities. Academic careers can sometimes be characterised by uncertainty in terms of job security, funding availability and the need to constantly adapt to evolving expectations and standards in academia.
What do you do in your free time?
I love hiking as it allows me to connect with nature and clear my mind. Travelling is another passion of mine: to explore new places and cultures broadens my horizons and provides fresh perspectives. Additionally, photography is a hobby I cherish as it lets me capture and appreciate the beauty of the world around me.
Who or what inspires you?
I am deeply inspired by scientists who make a tangible difference in our world. Their continuous pursuit of knowledge and dedication to solving real-world problems exemplify the true spirit of scientific enquiry. What inspires me most, however, is the profound journey of uncovering the unseen. Each discovery reveals the vast expanse of the unknown, reminding us that the more we learn, the more we realise how much remains to be discovered.
What is your proudest achievement?
My proudest achievement is becoming a full professor at such a prestigious university as UvA. As a female Egyptian, this journey has not been easy. Reaching this milestone is a testament to overcoming numerous challenges, and it allows me to serve as a role model for others from similar backgrounds.
emily.dixon@timeshighereducation.com
CV
1996-2001?Bachelor’s in pharmaceutical sciences, Alexandria University
2004-06?Master’s in cellular and molecular biotechnology, Wageningen University
2007-12?PhD in microbiology, Wageningen
2012?Postdoc, laboratory of microbiology, Wageningen
2012-13?Postdoc, Marie Curie fellowship, European Institute of Oncology
2013-14?Lecturer, department of pharmaceutical biotechnology, Genetic Engineering and Biotechnology Research Institute
2014-15?Postdoc, department of neurogastroenterology, University College Cork
2015?Associate specialist, host-microbe interaction group, Nestlé Research Centre?
2015-20?Assistant professor, department of microbial physiology, University of Groningen
2020?Athena Award
2020-24?Associate professor, department of microbial physiology, Groningen
2024-present?Professor?of microbiome engineering, University of Amsterdam
Appointments
Andy Schofield, currently vice-chancellor of Lancaster University, will be the next principal of the University of Glasgow. The theoretical physicist will join Glasgow in September 2025 on the retirement of Sir Anton Muscatelli. Gavin Stewart, Glasgow’s convenor of court, said Professor Schofield had “an exceptional academic record, along with the strategic vision and extensive leadership experience required to open the next successful chapter in our long and distinguished history”.
Bill Shorten, the former leader of Australia’s Labor Party, will be the next vice-chancellor of the University of Canberra. Currently minister for the national disability insurance scheme and government services, he will take up the role in February, with former vice-chancellor Stephen Parker leading the institution on an interim basis until then. Lisa Paul, Canberra’s chancellor, said that Mr Shorten “exemplifies the values of offering opportunity to all and reducing inequalities”.
Claire Aindow?is joining the University of Cumbria as pro vice-chancellor (growth and development). She is currently head of academic partnerships at Ravensbourne University London. Cumbria has also appointed?Zulf Ali?as pro vice-chancellor (research and knowledge exchange),?Cathy Lambert?as pro vice-chancellor (student journey and academic registrar) and?Tracey Slaven?as chief transformation officer.
Jacqui Glass?has been named dean of the Bartlett Faculty of the Built Environment at UCL, having held the position on an interim basis since April.
Saba Bebawi?will be the next dean of the School of Humanities and Communication Arts at Western Sydney University. She is currently head of journalism and writing at the University of Technology Sydney.
Emma Williams?has joined Anglia Ruskin University as director of its Centre of Excellence for Equity in Uniformed Public Services. She previously headed the Centre for Policing Research and Learning at the Open University.